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When dealing with weight loss and the people who go through it one should err to the side of caution and let the FDA do its job and demand some study be done so your public recognizes the side effects and risks of the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say everything to keep people on his or her medications. Researchers found that participants taking this drug for any year, lost weight within four weeks and have kept the extra weight off through the 56 weeks with the study. Contrave is a combination with the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which are made up of multiple active ingredient, which might make them far better and safer. Combo-pilling could be the newest fad or also the newest to come under scrutiny and so it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular will be the fact that by right now there aren't long term prescription slimming capsules that have been licensed by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug also can raise hypertension and heartbeat, and must not be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure level and heartbeat and must 't be used in patients with uncontrolled high hypertension, in addition to by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients for the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking. 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